أورام الدم

Hematology
No.Study TitlePrinciple InvestigatorSponsorTypeRecruitingStudy status
1REACH 3 study: A phase III randomized open-label multi-center study of ruxolitinib vs. best available therapy in patients with  corticosteroid-refractory chronic graft vs host disease after allogenic stem cell transplantation.Dr. Husam Abu JazarNovartisClinical TrialNo Ongoing
2Safety and Efficacy of Dasatinib 50 mg in First Line Treatment of Early Chronic Phase Chronic Myeloid Leukemia.Dr. Kamal Al-RabiHikmaClinical TrialYesOngoing
3A phase II, open-label, single arm study to evaluate the safety, efficacy, and pharmacokinetics of twice daily midostaurin (PKC412) combined with standard chemotherapy and as a single agent post-consolidation therapy in children with untreated FLT3-mutated AML.Dr. Mayada Abu ShanabNovartisClinical TrialNoPending
4CAR T - NHL : A phase II Study of CART Cell (MB-CART19.1) in Patients with Relapsed or Refractory CD19 Positive NHLDr. Khalid HalahlehKHCC
5CPKC412A2218 Novartis: A phase II, open-label, single arm study to evaluate the safety, efficacy, and pharmacokinetics of twice daily midostaurin (PKC412) combined with standard chemotherapy and as a single agent post-consolidation therapy in children with untreated FLT3-mutated AML

Dr. Mayada Abu Shanab

Novartis
6Ferinject: The Role of Iron Therapy Administration in optimizing Pre-operative anemia among Oncology Patients before Elective Major Surgery. A Clinical Trial StudyDr. Mahmoud Al MasriKHCC
7CAR T – ALL: MB-CART19.1 in patient with relapsed - refractory CD19 positive B cell acute lymphoblastic leukemia: A feasibility studyDr. Zaid Abdelrahman & Dr. Hasan HashemKHCC
8DOMAIN: A Multicenter Observational Study to Understand the Clinical Characteristics, Treatment Patterns and Access to Novel Therapies of Patients with Diffuse Large B-Cell Lymphoma in the MEA RegionDr. Mohammad Ma'kosehAstraZeneca
9HOPE: A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 3 Clinical Study to Assess Efficacy and Safety of Ropeginterferon alfa-2b (P1101) in Adult Patients with Pre-fibrotic/Early Primary Myelofibrosis or Overt Primary Myelofibrosis at Low or Intermediate-1 Risk According to DIPSS Plus (HOPE-PMF): The Core Study and Its Extension StudyDr. Waleed Da'naPharmaEssentia